WCB and MCB
WCB (Working Cell Bank) and MCB (Master Cell Bank) are critical components of the manufacturing process for biopharmaceuticals, particularly in the production of therapeutic proteins and monoclonal antibodies. They represent…
GLP-Compliant Cell
GLP (Good Laboratory Practice) compliance refers to a set of principles, guidelines, and regulations designed to ensure the quality, reliability, and reproducibility of non-clinical laboratory studies. GLP compliance is crucial…
Contamination
Contamination in cell culture refers to the presence of unwanted substances, microorganisms, or cells that can adversely affect the growth, health, and behavior of the cultured cells. Contamination can lead…
RNAi Cell Lines
RNA interference (RNAi) cell lines are genetically engineered cell lines in which a specific gene has been targeted for silencing or knockdown using RNAi technology. RNAi is a naturally occurring…
Protein-Overexpression
Protein overexpression is a molecular biology technique used to produce large amounts of a specific protein by manipulating a host organism or cell line to synthesize the desired protein in…
Avian Cell Lines
Avian cell lines are populations of cells derived from birds and cultured in vitro (in a laboratory setting) for various research and industrial applications. These cell lines have unique characteristics…
Insect Cell Lines
Insect cell lines are populations of insect cells that are cultured in vitro (in a laboratory setting) for various research and industrial applications. These cell lines are particularly useful for…
Mammalian Cell Lines
Mammalian cell lines are populations of cells derived from mammals that are cultured in vitro (in a laboratory setting) and used for various research and industrial applications. Mammalian cell lines…
Stem Cell Lines
Stem cell lines are populations of stem cells that are maintained in vitro (outside the body, usually in a laboratory) through a process of self-renewal and differentiation. Stem cells are…
Working Cell Banks
A Working Cell Bank (WCB) is a collection of cells derived from a Master Cell Bank (MCB) and used in the manufacturing process of biopharmaceutical products, such as vaccines, gene…